Can I take a uni-body (grand am) and fabricate a frame to where I can drop in a 350SB?

I want to find or fabricate a frame that can be mounted on a 2004 grand am GT. I have most of the interior and body complete, rear end tubed, and plenty of space in the engine bay. I am curious if anyone has attempted this and if so what their out come was. The car is no longer driven on roads, 1/4 track only so laws are out the window.